Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress

Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress

Oxidative stress can cause DNA breaks which induce activation of the DNA nick sensor enzyme poly(ADP-ribose) polymerase-1 (PARP-1), part of the 17 member PARP enzyme family. PARP-1 modifies target proteins by attaching to them several NAD-derived ADP-ribose units forming poly(ADP-ribose) (PAR) polymers. PARylation controls many cellular processes while intense PARylation may also lead to cell d...

PolyADP-ribosylation is involved in neurotrophic activity.

PolyADP-ribosylation is a transient posttranslational modification of proteins, mainly catalyzed by poly(ADP-ribose)polymerase-1 (PARP-1). This highly conserved nuclear protein is activated rapidly in response to DNA nick formation and promotes a fast DNA repair. Here, we examine a possible association between polyADP-ribosylation and the activity of neurotrophins and neuroprotective peptides t...

Inputs and Outputs in Islamic Banking System

Evaluation of performance and productivity is among the fundamental concepts inmanagement. In order to achieve their goals, organizations must evaluate theirperformance. One of the important stages of performance appraisal is evaluation oforganization’s efficiency. Banks, financial and credit institutions are among the mostimportant organizations of every economic system, because every activity...

PolyADP-Ribosylation in Postfertilization and Genome Reprogramming: Implications for Carcinogenesis

Inputs and Outputs Estimation in Inverse DEA

The present study addresses the following question: if among a group of decision making units, the decision maker is required to increase inputs and outputs to a particular unit in which the DMU, with respect to other DMUs, maintains or improves its current efficiencylevel, how much should the inputs and outputs of the DMU increase? This question is considered as a problem of inverse data envel...